Efficient Infectious Cell Culture Systems of the Hepatitis C Virus (HCV) Prototype Strains HCV-1 and H77

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Efficient infectious cell culture systems of the hepatitis C virus (HCV) prototype strains HCV-1 and H77.

UNLABELLED The first discovered and sequenced hepatitis C virus (HCV) genome and the first in vivo infectious HCV clones originated from the HCV prototype strains HCV-1 and H77, respectively, both widely used in research of this important human pathogen. In the present study, we developed efficient infectious cell culture systems for these genotype 1a strains by using the HCV-1/SF9_A and H77C i...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2014

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.02877-14